BENZYL ALCOHOL
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BENZYL ALCOHOL

BENZYL ALCOHOL


Product Description

BENZYL ALCOHOL is an important aromatic alcohol widely used in pharmaceutical, daily chemical, food and industrial fields, renowned for its strong polarity, low toxicity and good solubility.
  1. Basic Information
    Molecular Formula: ()
    Molecular Weight: 108.14
    CAS No.: 100-51-6
    Synonyms: Benzyl alcohol, α-hydroxytoluene, phenylmethanol
  2. Physical Properties
    Appearance: Colorless transparent liquid with a faint aromatic odor
    Melting Point: -15.3℃
    Boiling Point: 205.3℃
    Density: 1.045 g/mL (25℃)
    Solubility: Slightly soluble in water (4.29 g/100 mL, 20℃), miscible with organic solvents such as ethanol, ether, acetone and benzene
    Flash Point: 100℃ (closed cup)
    Vapor Pressure: 0.13 kPa (58℃)
  3. Chemical Properties
    Oxidation Reaction: Easily oxidized to benzaldehyde and further to benzoic acid
    Esterification Reaction: Reacts with organic acids to form benzyl esters, which are important intermediates for fragrances and plasticizers
    Halogenation Reaction: Reacts with hydrohalic acids and phosphorus halides to form benzyl halides (common alkylating agents)
    Stability: Stable at room temperature; prone to oxidation upon prolonged storage to produce benzaldehyde (with a bitter almond odor)
  4. Main Applications
  5. Pharmaceutical Field
    Injection Solvent/Analgesic: Reduces injection pain, e.g., as a solvent for spectinomycin
    Local Anesthesia/Antisepsis: Preservative for topical preparations, eye drops and injections
    Head Lice Treatment: For head lice infestations in patients aged 6 months and above
  6. Daily Chemicals and Fragrances
    Perfumes and Cosmetics: Solvent, fixative and preservative
    Flavor Raw Material: Used in floral fragrances such as jasmine and hyacinth
  7. Food Industry
    Food Additive (E1519): Preservative and flavor enhancer
    Applications: Candies, baked goods, beverages, chewing gum, etc.
  8. Industrial Applications
    Solvent: Coatings, inks, epoxy resins, adhesives, cleaning agents
    Organic Synthesis: Preparation of benzyl esters, benzyl ethers, dyes and pharmaceutical intermediates
    Plasticizer: Used in the processing of cellulose esters and resins
  9. Safety
    Toxicity: Low toxicity (Cramer Class I), with certain toxicity upon oral or dermal absorption
    Irritation: Irritating to skin, eyes and mucous membranes, may cause contact dermatitis
    Contraindication: Prohibited for intramuscular injection in neonates (may cause gasping syndrome)
    Storage: Cool, well-ventilated, sealed, away from fire sources and oxidizing agents
  10. Natural Sources
    Naturally occurs in essential oils such as jasmine, hyacinth and ylang-ylang, as well as in fruits and tea leaves, mostly in the form of esters.
  11. Industrial Preparation
    Chlorination-Hydrolysis Method (Mainstream): Toluene is chlorinated to form benzyl chloride, which is then hydrolyzed to obtain benzyl alcohol
    Cannizzaro Reaction: Benzaldehyde undergoes disproportionation in alkali to produce benzyl alcohol and benzoic acid

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